Curriculum Vitae of Francisco Bezanilla, Ph.D.

EDUCATION:

PROFESSIONAL EXPERIENCE:

 

1964-1968	Instructor in Physics, School of Medicine, Catholic University, Chile.
1965-1969	Instructor, Laboratory of Neurophysiology, Catholic University, Chile.
1969	Postdoctoral Fellow (Biophysics), Laboratory of Biophysics, NINCDS, NIH, Bethesda, MD
1969-1971	Postdoctoral Fellow, Department of Physiology, University of Rochester, N.Y.
1972-1974	Assistant Professor, Department of Biology, Faculty of Sciences, University of Chile
1974	Research Associate, Department of Physiology, University of Rochester School of Medicine
1974-1977	Professor, Department of Biology, Faculty of Sciences, University of Chile
1975-1976	Visiting Assistant Professor, Dept. of Physiol., Univ. of Pennsylvania School of Medicine
1977-2005	Professor of Neuroscience, Department of Physiology, UCLA
2006-2023	Professor, Institute for Molecular Pediatric Sciences and Dept. of Biochemistry and Molecular Biology, University of Chicago.
2023-	Professor Emeritus, Dept. of Biochemistry and Molecular Biology, University of Chicago.

 

HONORS:

 

1968-1969	Chilean Council for Scientific Research
1969	Visiting Fellow, NIH
1969-1971	Fellow Rockefeller Foundation
1977	Professor Rosenblueth Lecturer (I.P.N., Mexico)
1984-1986	Executive Committee, Biophysical Society
1985-1987	Council Member, Society of General Physiologists
1986-1987	Secretary of SOBLA
1990	Keneth S. Cole Award
1990	Society of General Physiologists Plenary Lecturer
1992	The Third Magoun Lecture, Brain Research Institute, UCLA
1998	Appointed as Leslie Scholar in Neuroscience
1994	American Physiological Society Annual  Lecturer
1995	Appointed as Susumu Hagiwara Professor of Neuroscience
1999	Fellow of the Biophysical Society
2000	Annual Review Prize Lecture, The Physiological Society, U.K.
2002	Elected to the Latin American Academy of Sciences
2006	Elected to United States Academy of Sciences
2007	Doctor Honoris Causa University of Antwerp, Belgium & A.R. Martin Lecture
2008	Lillian Eichelberger Cannon Professor
2013-2014	President Biophysical Society
2014	Doctor Honoris Causa Universidad de Valparaiso, Chile
2014	Fellow AAAS
2015	The Hille Lecture, University of Washington
2016	The 8th Annual Koster Lecture, Washington University in St. Louis.
2019	Elected member of the American Academy of Arts and Sciences.

 

RESEARCH INTERESTS:

Biophysics of excitation: Structure Function in Voltage Dependent Membrane Proteins

LIST OF PUBLICATIONS:

1. Rojas,E., R.E. Taylor, I. Atwater and F. Bezanilla (1969). Analysis of the effects of calcium or magnesium on voltage-clamped currents in perfused squid axons bathed in solutions of high potassium. J. Gen. Physiol. 54:532-552. 
2. Atwater, I., F. Bezanilla and E. Rojas (1969). Sodium influxes in internally perfused squid giant axon during voltage clamp. J. Physiol. (Lond) 201:657-664. 
3. Bezanilla, F., E. Rojas and R.E. Taylor (1970). Time course of the sodium influx in squid giant axon during a single voltage clamp pulse. J. Physiol. (Lond) 207:151-164 
4. Rojas, E. F. Bezanilla and R.E. Taylor (1970). Demonstration of sodium and potassium conductance changes during a nerve action potential. Nature 225:747-748. 
5. Bezanilla, F. E. Rojas and R.E. Taylor (1970). Sodium and potassium conductance changes during a membrane action potential. J. Physiol (Lond) 211:729-751. 
6. Atwater, I., F. Bezanilla and E. Rojas (1970). Time course of the sodium permeability change during a single membrane action potential. J. Physiol (Lond) 211:753-765. 
7. Rojas, E., I. Atwater and F. Bezanilla (1970). Fixed charge structure of the squid axon membrane. In: Permeability and Function of Biological Membranes, Liana Bolix, A. Katchalsky, R.D. Keynes, W.R. Loewenstein and B.A. Pethica, eds. 
8. Cole, K.S., R. Guttman and F. Bezanilla (1970). Nerve excitation without threshold. Proc. Natl. Acad. Sci. (USA) 65:884-891. 
9. Bezanilla, F., C. Caputo and P. Horowicz (1971). Voltage Clamp Activation of Contraction in Striated muscle fibers of the frog. Acta Cientif. Venezolano 22:Sippl 2:72-74. 
10. Bezanilla, F., C. Caputo, H. Gonzalez-Serratos and R.A. Venosa (1972). Sodium dependence of the inward spread of activation in isolated twitch muscle fibers of the frog. J. Physiol (Lond) 223:507-523. 
11. Bezanilla, F. and C.M. Armstrong (1972). Negative conductance caused by entry of sodium and cesium into the potassium channels of the squid axon. J. Gen. Physiol. 60:588-608. 
12. Armstrong, C.M., F. Bezanilla and P. Horowicz (1972). Twitches in the presence of EGTA. Biochim. Biophys. Acta 267:605-608. 
13. Armstrong, C.M. and F. Bezanilla (1973). Currents related to movement of the gating particles of the sodium channels. Nature 242:459-461. 
14. Armstrong, C.M., F. Bezanilla and E. Rojas (1973). Destruction of sodium conductance inactivation in squid axons perused with pronase. J. Gen. Physiol. (Lond) 62:375-391. 
15. Bezanilla, F., E. Rojas and J. Vergara (1973). Excitation-contraction coupling in barnacle muscle fibers under membrane potential control. Acta Phisiol. Latinoamericana 23:497-501. 
16. Bezanilla, F. and C.M. Armstrong (1974). Gating currents of the sodium channels: three ways to block them. Science 183:753-754. 
17. Armstrong, C.M. and F. Bezanilla (1974). Charge movement associated with the opening and closing of the activation gates of the sodium channels. J. Gen. Physiol. 63:533-552. 
18. Bezanilla, F. and C.M. Armstrong (1975). Kinetic properties and inactivation of the gating currents of sodium channels in squid axon. Phil. Trans. R. Soc. Lond. B 270:365-375. 
19. Bezanilla, F. and P. Horowicz (1975). Fluorescence intensity changes associated with the contractile activation in frog muscle stained with Nile Blue A. J. Physiol. 246:709-735. 
20. Armstrong, C.M. and F. Bezanilla (1975). Current associated with the ionic gating structures in nerve membranes. Ann. N.Y. Acad. Sci. 274:265-277. 
21. Bezanilla, F. and C.M. Armstrong (1976). Properties of the sodium channel gating currents. Cold Spring Harbor Symposia on Quantitative Biology XL:297-304. 
22. Vergara, J. and F. Bezanilla (1976). Fluorescence changes during electrical activity in frog muscle stained with merocyanine. Nature 259:684-686. 
23. Bezanilla, F. and C.M. Armstrong (1977). A low cost signal averager and data acquisition device. Am. J. Physiol. 232(3):C211-C215. 
24. Bezanilla, F. and C.M. Armstrong (1977). Inactivation of the sodium channel. I. Sodium current experiments. J. Gen. Physiol. 70:549-566. 
25. Armstrong, C.M. and F. Bezanilla (1977). Inactivation of the sodium channel. II. Gating current experiments. J. Gen. Physiol. 70:567-590. 
26. Bezanilla, F. and J. Vergara (1978). Fluorescence signals from skeletal muscle fibers. In: Biophysical Aspects of Cardiac Muscle. M. Morad, Ed. Academic Press, New York, pp. 229-254. 
27. Vergara, J., F. Bezanilla and B.M. Salzberg (1978). Nile Blue fluorescence signals from cut single muscle fibers under voltage or current clamp conditions. J. Gen. Physiol. 72:775-800. 
28. Bezanilla, F. and R.E. Taylor (1978). Temperature effects on gating currents in the squid giant axon. Biophys. J. 23:479-484. 
29. Caputo, C., J. Vergara and F. Bezanilla (1979). Local anaesthetics inhibit tension development and Nile Blue fluorescence signals in frog skeletal muscle fibers. Nature 277:401-402. 
30. Taylor, R.E. and F. Bezanilla (1979). Comments on the measurement of gating currents in the frequency domain. Biophys. J. 26:338-340. 
31. Taylor, R.E., F. Bezanilla and E. Rojas (1980). Diffusion models for the squid axon Schwann cell layer. Biophys. J. 29:95-118. 
32. Bezanilla, F. and J. Vergara (1980). Properties of Excitable membranes. In: "Membrane structure and Function." E.E. Bittar, Ed. Vol. II, Ch. 2. J. Wiley & Sons, New York, pp. 53-113. 
33. Llano, I. and F. Bezanilla (1980). Current recorded from a cut-open giant axon under voltage clamp. Proc. Natl. Acad. Sci. (USA) 77:7484-7486. 
34. Vergara, J. and F. Bezanilla (1981). Optical Studies of E-C coupling with potentiometric dyes. In: "Regulation of Muscle contraction:Excitation-contraction coupling," Alan D. Grinnell and Mary A.B. Brazier, Eds., Academic Press, New York, pp. 67-77. 
35. Taylor, R.E., J.M. Fernandez and F. Bezanilla (1981). Squid axon membrane low-frequency dielectric properties. In: "The Biophysical Approach to Excitable System," W.J. Adelman, Jr. and D.E. Goldman, Eds., Plenum Publishing Corporation, New York, pp. 97-106. 
36. Bezanilla, F. and J. Vergara (1982). Optical studies of excitation-contraction coupling on muscle. In: Diseases of the Motor Unit: Sixth International Conference sponsored by the Muscular Dystrophy Association, D.L. Schotland, M.D., Ed., J. Wiley & Sons, Inc., New York, 20:445-511. 
37. Bezanilla, F. (1982). Gating charge movements and kinetics of excitable proteins. In: Proteins of the Nervous System, Structure and Function, B. Haber, J.R. Perez-Polo, and J.D. Coulter, Eds., Alan R. Liss, Inc., New York, pp. 3-16. 
38. Bezanilla, F. R.E. Taylor and J.M. Fernandez (1982). Distribution and kinetics of membrane dielectric polarization. I. Long term inactivation of gating currents. J. Gen. Physiol. 79:21-40. 
39. Fernandez, J.M., F. Bezanilla and R.E. Taylor (1982). Distribution and kinetics of membrane dielectric polarization. II. Frequency domain studies of gating currents. J. Gen. Physiol. 79:41-69. 
40. Bezanilla, F., M.M. White and R.E. Taylor (1982). Gating currents associated with potassium channel activation. Nature 296:657-659. 
41. Fernandez, J.M., F. Bezanilla and R.E. Taylor (1982). Effect of chloroform on the movement of charges within the nerve membrane. Nature 297:150-152. 
42. Bezanilla, F. and R.E. Taylor (1982). Voltage dependent gating of sodium channels. In: Abnormal Nerve and Muscle as Abnormal Impulse generators, W. Culp and J. Ochoa, Eds., Oxford University Press, New York, pp. 62-79. 
43. Bezanilla, F. J. Vergara and R.E. Taylor (1982). Voltage clamping of excitable membranes. In: Methods of Experimental Physics. G. Ehrenstein and H. Lecar, Eds. Vol. 20, pp. 445-511. 
44. DiPolo, R. C. Caputo and F. Bezanilla (1983). Voltage dependent calcium channel in the squid axon. Proc. Natl. Acad. Sci. (USA) 80:1743-1745. 
45. Taylor, R.E. and F. Bezanilla (1983). Sodium and gating current time shifts resulting from changes in initial conditions. J. Gen. Physiol. 81:773-784. 
46. Fernandez, J.M., F. Bezanilla and R.E. Taylor (1983). Induced capacitance in the squid giant axon. Lipophilic ion displacement currents. J. Gen. Physiol. 82:331-346. 
47. Salzberg, B.M. and F. Bezanilla (1983). An optical determination of the series resistance in Loligo. J. Gen. Physiol. 82:807-817. 
48. Llano, I. and F. Bezanilla (1983). Analysis of sodium current fluctuations in the cut-open squid giant axon. J. Gen. Physiol. 83:133-142. 
49. Caputo, C., F. Bezanilla and P. Horowicz (1984). Depolarization-contraction coupling in short frog muscle fibers. A voltage clamp study. J. Gen. Physiol. 84:133-154. 
50. Leow, L.M., Cohen, L.B., Salzberg, B.M., Obaid, A.L. and Bezanilla, F. (1985). Charge-shift probes of membrane potential. Characterization of Aminostrylpyridinium dyes on the squid giant axon. Biophys. J. 47:71-77. 
51. Stimers, J., Bezanilla, F. and Taylor, R.E. (1985). Sodium channel activation in the squid giant axon. J. Gen. Physiol. 85:65-82. 
52. Bezanilla, F. (1985). A high capacity data recording device based on a digital audio processor and a video cassette recorder. Biophys. J. 47:437-441. 
53. White, M. and Bezanilla, F. (1985). Activation of squid axon K channels. J. Gen. Physiol. 85:539-554. 
54. DiPolo, R., Bezanilla, F., Caputo, C. and Rojas, H. (1985). Voltage dependence of the Na/Ca in voltage-clamped dialyzed squid axons. J. Gen. Physiol. 86:457-478. 
55. Bezanilla, F. (1985). Gating of sodium and potassium channels. J. Membrane Biology. 88:97-111. 
56. Bezanilla, F. (1986). Voltage dependent gating: gating current measurement and interpretation. In: Ionic Channels in Cells and Model Systems. R. Latorre, ed., Plenum Publ. Co. 
57. Bezanilla, F. and White, M.M. (1986). Properties of ionic channels in excitable membranes. In: Physiology of Membrane Disorders. T. Andreoli, J. Hoffman, Fanestil, and S. Schultz, eds., Plenum Publ. Co., Chapter 27, pp. 437-448. 
58. Bezanilla, F., Caputo, C., DiPolo, R. and Rojas, H. (1986). Potassium conductance of the squid giant axon is modulated by ATP. Proc. Natl. Acad. Sci. USA 83:2743-2745. 
59. Stimers, J.R., Bezanilla, F. and Taylor, R.E. (1987). Sodium channel gating currents. Origin of the rising phase. J. Gen. Physiol. 89:521-540. 
60. Bezanilla, F. (1987). Single sodium channels from the squid giant axon. Biophys. J. 52:1087-1090. 
61. Llano, I., Webb, C.K. and Bezanilla, F. (1987). Potassium conductance of the squid giant axon. Single channel studies. J. Gen. Physiol. 92:179-196. 
62. Perozo, E., Webb, C.K. and Bezanilla, F. (1988). Modulation of the potassium conductance in the squid giant axon. In: Calcium and Ion Channel Modulation, Alan Grinnell, David Armstrong, and Meyer B. Jackson, eds., Plenum Press Publishing, pp. 229-237. 
63. Behrens, I., Oberhauser, A., Bezanilla, F., and Latorre, R. (1989). Batrachotoxin-modified sodium channels from squid optic nerve in planar bilayers. Ion conduction and gating properties. J. Gen. Physiol. 93:23-41. 
64. Perozo, E., Bezanilla, F. and DiPolo, R. (1989). Modulation of K channels in dialyzed squid axons: ATP-mediated phosphorylation. J. Gen. Physiol. 93:1195-1218. 
65. Caputo, C., Bezanilla, F. and DiPolo, R. (1989). Currents related to the sodium-calcium exchange in squid giant axon. Biochim. Biophys. Acta 986:250-256. 
66. Agustine, C.K. and Bezanilla, F. (1989). Phosphorylation modulates potassium conductance and gating current of perfused giant axons of squid. J. Gen. Physiol. 95:242-272. 
67. Bezanilla, F. and C. Vandenberg (1990). The cut-open axon technique. In: Squid as Experimental Animals, Daniel L. Gilbert, W.J. Adelman, Jr., and J.M. Arnold, eds., Plenum Publishing Corporation, pp. 153-159. 
68. Correa, A.M., F. Bezanilla and W.S. Agnew (1990). Voltage activation of purified eel sodium channels reconstituted into artificial liposomes. Biochemistry 29:6230-6240. 
69. Zimmerberg, J., F. Bezanilla and V.A. Parsegian (1990). Solute inaccessible aqueous volume changes during opening of the potassium channel of the squid giant axon. Biophys. J. 57:1049-1064. 
70. Perozo, E. and F. Bezanilla (1990). Phosphorylation affects voltage gating of the delayed rectifier K channel by electrostatic interactions. Neuron 5:685-690. 
71. Perozo, E. and F. Bezanilla (1991). Phosphorylation of K channels in the squid giant axon: A mechanistic analysis. J. Bioenerg. & Biomemb. 23:599-613. 
72. Perozo, E. C.A. Vandenberg, D.S. Jong and F. Bezanilla (1991). Single channel studies of the phosphorylation of K channels in the squid giant axon. I. Steady-state conditions. J. Gen. Physiol. 98:1-18. 
73. Perozo, E., D.S. Jong and F. Bezanilla (1991). Single channel studies of the phosphorylation of K channels in the squid giant axon. II. Nonstationary conditions. J. Gen. Physiol. 98:19-34. 
74. Correa, A.M., R. Latorre and F. Bezanilla (1991). Ion permeation in normal and Batrachotoxin-modified Na channels in the squid giant axon. J. Gen. Physiol. 97:606-625. 
75. Mathes, C., F. Bezanilla and R.E. Weiss (1991). Sodium current and membrane potential in EDL muscle fibers from normal and dystrophic (mdx) mice. Am. J. Physiol. 261:C718-C725. 
76. Bezanilla, F., E. Perozo, D.M. Papazian and E. Stefani (1991). Molecular basis of gating charge immobilization in Shaker potassium channels. Science 254:679-683. 
77. Vandenberg, C.A. and F. Bezanilla (1991). Single-channel, macroscopic and gating currents from sodium channels in the squid giant axon. Biophys. J. 60:1499-1510. 
78. Vandenberg, C.A. and F. Bezanilla (1991). A sodium channel model of gating based on single channel, macroscopic ionic and gating currents in the squid giant axon. Biophys. J. 60:1511-1533. 
79. Perozo, E., D.M. Papazian, E. Stefani and F. Bezanilla (1992). Gating currents in Shaker K channels. Implications for activation and inactivation models. Biophys. J. 62:160-171. 
80. Correa, A.M., Bezanilla, F. and Latorre, R. (1992). Gating kinetics of Batrachotoxin-modified Na channels in the squid giant axon. Voltage and temperature effects. Biophys. J. 61:1332-1352. 
81. Perozo, E., MacKinnon, R., Bezanilla, F. and Stefani, E. (1993). Gating currents from a non-conducting mutant reveal open-closed conformations in Shaker K⁺ channels. Neuron. 11:353-358. 
82. Salzberg, B.M., A.L. Obaid and F. Bezanilla (1993). Microsecond response of a voltage-sensitive merocyanine dye:fast voltage-clamp measurements on squid giant axon. Japanese Journal of Physiology 43, Suppl 1, S37-S41. 
83. Perozo, E., Santacruz-Toloza, L., Stefani, E., Bezanilla, F., and Papazian, D. (1994). S4 mutations alter gating currents of Shaker K channels. Biophys. J. 66:345-354. 
84. Stefani, E., Toro, L., Perozo, E. and F. Bezanilla (1994). Gating of Shaker K channels. I. Ionic and gating currents. Biophys. J. 66:996-1010. 
85. Bezanilla, F., Perozo, E. and E. Stefani (1994). Gating of Shaker K channels. II. The components of gating currents and a model of channel activation. Biophys. J. 66:1011-1021. 
86. Sigg, D., Stefani, E. and F. Bezanilla (1994). Gating current noise produced by elementary transitions in shaker potassium channels. Science. 264:578-582. 
87. Bezanilla, F. and E. Stefani (1994). Voltage dependent gating in ionic channels. Ann. Rev. Biophys. and Molec. Structure. 23:819-846. 
88. Correa, A.M. and F. Bezanilla (1994). Gating of the squid sodium channels at positive potentials. I. Macroscopic ionic and gating currents. Biophys. J. 66:1853-1863. 
89. Correa, A.M. and F. Bezanilla (1994). Gating of the squid sodium channels at positive potentials. II. Single channels reveal two open states. Biophys. J. 66:1864-1878. 
90. Stefani, E., Toro, L., Perozo, E. and F. Bezanilla (1994). Gating currents of cloned Shaker K channels. In "Handbook of membrane channels. Molecular and cellular physiology," C. Peracchia, Ed. Academic Press Inc., pp. 29-40. 
91. Caputo, C., E. Perozo and F. Bezanilla. (1994). Chemical modification of squid axon K⁺ channel -SH groups with the organic mercurial compound p-hydroxymercuriphenylsulfonic acid (PHMPS) . Pflugers Arch. 428:315-322.
92. Zampighi, G.A., M. Kreman, K.J. Boorer, D.D.F. Loo, F. Bezanilla, G. Chandy, J.E. Hall, E. M. Wright. (1995). A Method for determining the unitary functional capacity of cloned channels and transporters expressed in Xenopus laevis oocytes. J. Membrane Biol. 148:65-78.
93. Hocherman, S. and F. Bezanilla (1996). Delayed rectifier currents in skeletal muscle of control and mdx mice. J. Physiol (Lond.) 493.1:113-128.
94. Bezanilla, F. and E. Stefani. (1996). Gating of the Shaker B Potassium Channel. In "Basic Neuroscience in invertebrates." Edited by H. Koike, Y. Kidokoro, K. Takahashi and T. Kanaseki. Japan Scientific Societies. Tokyo.
95. Seoh, S.-A., D. Sigg, D.M. Papazian and F. Bezanilla. (1996). Voltage-sensing residues in the S2 and S4 segments of the Shaker K⁺ channel. Neuron. 16:1159-1167. 
96. Rodriguez, B.M., and F. Bezanilla. (1996) Transitions near the open state in Shaker K⁺-channel: Probing with temperature.  Neuropharmacology. 35: 775-785. 
97. Sigg, D., and F. Bezanilla. (1997). Total Charge Movement per Channel. The Relation between Gating Charge Displacement and the Voltage of Activation. J. Gen. Phys. 109:27-39.
98. Bezanilla, F, S.-A. Seoh, D. Sigg and D.M. Papazian. (1997). The molecular origin of voltage dependence in ionic channels. In "From ion channels to cell-to-cell conversation". Edited by Latorre and Saez, Plenum Press, New York.
99. Rakowski, R.F, F. Bezanilla, P. DeWeer, D. C. Gadsby, M. Holmgren and J. Wagg. (1997) Charge translocation by the Na/K pump. 834:231-243.
100. Patton, D.E., T. Silva and F. Bezanilla (1997). RNA Editing Generates a Diverse Array of Transcripts Encoding Squid Kv2 K+ Channels with Altered Functional Properties. Neuron 19:711-722.
101. Cha, A. and F. Bezanilla (1997) Characterizing Voltage-dependent Conformational Changes in The Shaker K+ channel with fluorescence. Neuron 19:1127-1140.
102. Olcese, R., R. Latorre, L. Toro, F. Bezanilla and E. Stefani (1997). Correlation between charge movement and ionic current during slow inactivation in Shaker K+ channels. J. Gen. Physiol. 110:579-590..
103. Papazian, D.M. and F. Bezanilla (1997). How does a channel sense voltage? News In Physiological Sciences 12:203-210.
104. Starace, D.M, E. Stefani and F. Bezanilla.(1997). Voltage-dependent Proton Transport by the Voltage Sensor of the Shaker K+ channel. Neuron 19:1319-1327.
105. Roux, M.J., R. Olcese, L. Toro, F. Bezanilla and E. Stefani. (1998). Fast Inactivation in Shaker K+ channels: properties of ionic and gating currents. J. Gen. Physiol. 111:625-638.
106. Rodriguez, B.M, D. Sigg and F. Bezanilla. (1998) Voltage Gating of Shaker K+ Channels. The Effect of Temperature on Ionic and Gating Currents J. Gen. Physiol. 112: 223-242.
107. Stefani, E. and F. Bezanilla (1998). The cut-open oocyte voltage clamp technique. Methods in Enzymology. 293:300-318.
108. Bezanilla, F. and E. Stefani (1998). Gating Currents. Methods in Enzymology 293:331-352.
109. Cha, A. and F. Bezanilla. (1998). Structural implications of fluorescence quenching in the Shaker K+ channel. J. Gen Physiol. 112:391-408.
110. Cha, A., N. Zerangue, M. Kavanaugh and F. Bezanilla. (1998) Fluorescence Techniques for studying cloned channels and transporters expressed in Xenopus oocytes. Methods in Enzymology. 296:566-578.
111. Stefani, E. and F. Bezanilla. (1999) Gating currents. Encyclopedia of Neuroscience. Elsevier Science. P 764-768.
112. Bezanilla, F. (1999) Squid axon. Encyclopedia of Neuroscience. Elsevier Science. P 1939-1942.
113. Cha, A., P.C. Ruben, A.L. George, E. Fujimoto, and F. Bezanilla (1999) Voltage sensors in domains III and IV, but not I and II, are immobilized by Na+ channel fast inactivation. Neuron 22:73-87.
114. Sigg, D., H. Qian and F. Bezanilla. (1999) Kramers’ diffusion theory applied to gating kinetics of voltage dependent channels. Biophys. J. 76:782-803.
115. Cha, A., G. Snyder, P.R. Selvin and F. Bezanilla.(1999) Atomic scale movement of the voltage-sensing region in a potassium channel measured via spectroscopy. Nature 402:809-813.
116. Bezanilla, F. (2000) The voltage sensor in voltage-dependent ion channels. Physiological Reviews. 80:555-592.
117. Gonzalez, C., Rosenman, E., Bezanilla, F. Alvarez, O., and Latorre, R. (2000) Modulation of the Shaker K+ Channel Kinetics by the S3-S4 Linker. J.Gen. Phys. 115:193-207.
118. Sorensen, J.B., Cha, A., Latorre, R., and Bezanilla, F. (2000) Deletion of the S3-S4 Linker in the Shaker Potassium Channel Reveals Two Quenching Groups Near the Outside of S4. J. Gen. Phys. 115:209-221.
119. Holmgren, M., J. Wagg, F. Bezanilla, R.F. Rakowski, P. De Weer, D. Gadsby. (2000) Three distinct and sequential steps in the release of sodium ions by the Na+ /K+ ATPase. Nature 403:898-901.
120. Tang, C-Y, F. Bezanilla and D.M. Papazian. (2000) Extracelullar Mg2+ modulates slow gating transitions and the opening of Drosophila ether-a-go-go potassium channels. J. Gen Physiol. 115:319-337.
121. Rosenthal, J.C and F. Bezanilla (2000) Seasonal Variation in Conduction Velocity of Action Potentials in Squid Giant Axons. Biol. Bull. 199: 135-143.
122. Olcese, R., D. Sigg, R. Latorre, F. Bezanilla and E. Stefani. (2001) A conducting state with properties of a slow inactivated state in a Shaker K+ channel mutant. J. Gen Physiol. 117: 149-163.
123. Dorine M. Starace and Francisco Bezanilla. (2001) Histidine Scanning Mutagenesis of Basic Residues of the S4 Segment of the Shaker K+ Channel. J. Gen. Physiol.117: 469-490.
124. Gonzalez, C., E. Rosenman, F. Bezanilla, O. Alvarez, and R. Latorre.(2001) Periodic Perturbations in Shaker K+ channel gating kinetics by deletions in the S3-S4 linker. Proc. Natl. Acad. Sci. 98: 9617-9623.
125. Pantoja, R., D. Sigg, R. Blunck, Francisco Bezanilla and James R. Heath. (2001) Bilayer reconstitution of Voltage-dependent Ion Channels using a microfabricated Silicon Chip. Biophys. J. 81: 2389-2394.
126. Rosenthal, J.J.C and F. Bezanilla (2002) Extensive Editing of mRNAs for the Squid Delayed Rectifier K+ Channel Regulates Subunit Tetramerization .Neuron 34: 743-757.
127. Rosenthal, J.J. and F. Bezanilla. (2002) A comparison of propagated action potentials from tropical and temperate squid axons: different durations and conduction velocities correlate with ionic conductance levels. J Exp Biol. 205:1819-30.
128. Bezanilla, F. (2002) Perspective: Voltage sensor movements. J. Gen. Physiol. 120:465-473.
129. Chanda, B. and F. Bezanilla (2002) Tracking voltage-dependent conformational changes in skeletal muscle sodium channel during activation. J. Gen. Physiol. 120: 629-645.
130. Bezanilla, F. and E. Perozo. (2002). Force and Voltage Sensors in One Structure. Science 298: 1562.
131. Asamoah, O. K., J.P. Wuskell, L. M. Loew, and F. Bezanilla (2003) A Fluorometric Approach to Local Electric Field Measurements in a Voltage-Gated Ion Channel. Neuron. 37:85-97.
132. Sigg, D. and F. Bezanilla. (2003). A Physical Model of Potassium Channel Activation: From Energy Landscape to Gating Kinetics. Biophys. J. 2003 84: 3703-3716.
133. Sigg, D., F. Bezanilla, and E. Stefani. (2003).Fast gating in the Shaker K+ channel and the energy landscape of activation. PNAS 100: 7611-7615.
134. Bezanilla, F. and E. Perozo. (2003) The voltage Sensor and the gate in ion channels. In Advances in Protein Chemistry, Vol 63.,D. Rees, ed. Elsevier Science.
135. Starace, D.M and F. Bezanilla (2004). A proton pore in a potassium channel voltage sensor reveals a focused electric field. Nature.427:548-552.
136. Chanda, B., Asamoah, O.K, and F. Bezanilla (2004) Coupling interactions between voltage sensors of the sodium channel as revelaed by site-specific measurements. J. Gen. Physiol. 123: 217-230.
137. Blunck, R., D. M. Starace, A.M. Correa, and F. Bezanilla. (2004) Detecting rearrangements of Shaker and NaChBac in real-time with fluorescence spectroscopy in patch-clamped mammalian cells. Biophys. J. 86: 3966-3980.
138. Ries, R.S., H. Choi, R. Blunck, F. Bezanilla and J.R Heath (2004) Black lipid membranes: visualizing structure, dynamics and substrate dependence of membranes. J. Phys.Chem. B 108:16040-16049.
139. Kuzmenkin, A., F. Bezanilla and A.M. Correa (2004).Gating of the bacterial sodium channel NaChBac: volatge dependent charge movement and gating currents. J.Gen.Physiol 124:349-356.
140. Bezanilla, F. (2004) RNA editing of a human potassium channel modifies its inactivation.N&V Nature Structure and Molecular Biology, 11:915-916.
141. Pantoja, R., J.M. Nagarah, D.M. Starace, N. Melosh, R. Blunck, F. Bezanilla and J.R. Heath.(2004). Silicon-based chip patch-clamp electrodes integrated with PDMS microfluidics. Biosensors and Biolectronics. 20: 509-517.
142. Dahan, D.S., M.I. Dibas, E.J. Petersson, V.C Auyeung, B. Chanda, F. Bezanilla, D. A. Dougherty and H. Lester. (2004). A fluorophore attached to nicotinic acetylcholine receptor bM2 detects productive binding of agonist to the ad site. PNAS 101: 10195-10200
143. Loo, D.F., B.A. Hirayama, A. Cha, F. Bezanilla and E. M. Wright (2004) Perturbation analysis of the voltage-sensitive conformational changes of the Na+/Glucose cotransporter. J. Gen. Physiol. 125: 13-36.
144. Bezanilla, F. (2005) Voltage-gated Ion Channels. IEEE Transactions on Nanobioscience 4:34-48.
145. Bezanilla, F. (2005) The voltage-sensor structure in a voltage-gated channel. Trends In Biochemical Sciences. 30:166-168.
146. Posson, D.J., P. Ge, C. Miller, F. Bezanilla and P.R. Selvin (2005) Small vertical movement of a K+ channel voltage sensor measured with luminescence energy transfer. Nature 436: 848-851.
147. Chanda, B., O.K.Asamoah, R. Blunck, B. Roux and F. Bezanilla (2005) Gating charge displacement in voltage-gated channels involves limited transmembrane movement. Nature 436: 852-856.
148. Bannister, J. P.A, B. Chanda, F. Bezanilla, and D. M. Papazian. (2005). Optical detection of rate-determining ion-modulated conformational changes of the ether-à-go-go K+ channel voltage sensor. PNAS 102, 18718-18723.
149. Bezanilla, F. (2005) The origin of subconductance levels in voltage-gated K+ channels. J. Gen. Physiol. 126: 83-86.
150. Chanda, B., R. Blunck, L. C. Faria, F. E. Schweizer, I. Mody & F. Bezanilla (2005). A hybrid approach to measuring electrical activity in genetically specified neurons. Nature Neuroscience 8, 1619 - 1626
151. Blunck, R., B. Chanda and F. Bezanilla. (2005) Nano to micro - Fluorescence measurements of electric field in molecules and genetically specified neurons. J. Memb. Biol. 208: 91 - 102
152. Jurisic, N. and F. Bezanilla (2006) Letter to Editor. J. Neurophysiol. 96:959.
153. Blunck, R., J. F. Cordero-Morales, L. G. Cuello, E. Perozo and F. Bezanilla (2006) Detection of the Opening of the Bundle Crossing in KcsA with Fluorescence Lifetime Spectroscopy reveals the Existence of two Gates for Ion Conduction. J.Gen.Physiol. 128: 569-581.
154. Richardson, J., R. Blunck, P. Ge, P.R. Selvin, F. Bezanilla, D.M.Papazian and A.M. Correa. (2006). Distance measurements reveal a common topology of prokaryotic voltage-gated ion channels in the lipid bilayer. PNAS 103:15865-15870.
155. Ben-Chain, Y, B. Chanda, N. Dascal, F. Bezanilla, I. Parnas and H. Parnas. (2006) Movement of 'gating charge' is coupled to ligand binding in a G-protein coupled receptor. Nature 444:106-109.
156. Bezanilla, F. (2006) The action potential:From voltage-gated conductances to molecular structures. Biological Research 39:425-435.
157. Bezanilla, F. (2006) Voltage-gated ion channels. In: Biological Membrane Ion Channels: Dynamics, Structure, and Applications (eds. S. H. Chung, O. S. Andersen and V. Krishnamurthy). Springer, New York. Chapter 3, Pp. 81-118.
158. Campos, F.V, B. Chanda, B. Roux, and F. Bezanilla (2007). Two atomic constraints unambiguously position the S4 segment relative to S1 and S2 segments in the closed state of Shaker K channel PNAS 104: 7904-7909.
159. Campos, F.V, B. Chanda, P. S.L. Beirão, and F. Bezanilla (2007) ß-Scorpion Toxin Modifies Gating Transitions in All Four Voltage Sensors of the Sodium Channel. J. Gen. Physiol. 130: 257-268.
160. Sandtner, W., F. Bezanilla, and A. M. Correa (2007) In Vivo Measurement of Intramolecular Distances Using Genetically Encoded Reporters. Biophys. J. 93: L45-L47.
161. Chanda, B. and F. Bezanilla (2008). A Common Pathway for Charge Transport through Voltage Sensing Domains. Neuron 57:345-351.
162. Bezanilla, F. (2008) How membrane proteins sense voltage. Nature Reviews Molecular Cell Biology. 9: 323-332.
163. Campos, F.V., B. Chanda, P.S.L. Beirao and F. Bezanilla (2008) Alpha-Scorpion Toxin Impairs a Conformational Change that Leads to Fast Inactivation of Muscle Sodium Channels. J. Gen Physiol. 132: 251-263.
164. Villalba-Galea, C.A, W. Sandtner, D. M. Starace and F. Bezanilla (2008) S4-based Voltage Sensors have three major conformations. PNAS 105:17600-17607.
165. Blunck, R., H. McGuire, H. C. Hyde and F. Bezanilla. Fluorescence detection of the movement of single KcsA subunits reveals cooperativity. PNAS 2008 105:20263-20268
166. Bezanilla, F. Ion Channels: From Conductance to Structure. Neuron 2008 60:456-468.
167. Villalba-Galea, C.A, W. Sandtner, D. Dimitrov, H. Mutoh, T Knöpfel and Francisco Bezanilla (2009). Charge Movement of a Voltage-Sensitive Fluorescent Protein. Biophys. J. 96, L19-L21. PMID: 19167283.
168. Rosenthal JJ, Seibel BA, Dymowska A, Bezanilla F. (2009) Trade-off between aerobic capacity and locomotor capability in an Antarctic pteropod. PNAS.106(15):6192-6. PMID: 19325127.
169. Gagnon, D. and F. Bezanilla (2009) A single voltage sensor is capable of gating the Shaker K+ channel. . J. Gen. Physiol.133:467-483. PMID: 19398775
170. Villalba-Galea, C.A., F. Miceli, M. Taglialatela, and F. Bezanilla (2009) Coupling between the voltage-sensing and phosphatase domains of Ci-VSP. J. Gen. Physiol. 134:5-14. PMID: 19564425.
171. Miceli, F., M.R. Cilio, M. Taglialatela and F. Bezanilla (2009) Gating currents from neuronal Kv7.4 channels. General features and correlation with the ionic conductance. Channels 3:4, 1-10.
172. Gagnon, D. and F. Bezanilla (2010). The contribution of individual subunits to the coupling of the voltage sensor to pore opening in Shaker K channels: effects of ILT mutations in heterotetramers. J. Gen. Physiol. 136:555-568.
173. Lacroix, J.J., A.J.Labro and F. Bezanilla (2011) Properties of deactivation gating currents in Shaker Channels. Biophys J. 100:L28-L30.
174. Lacroix, J.J. and F. Bezanilla (2011) Control of a final gating charge transition by a hydrophobic residue in the S2 segment of a K+ channel voltage sensor . PNAS 108:6444-6449.
175. Lacroix, J., C. R. Halaszovich, D. N. Schreiber, M.G. Leitner, F. Bezanilla, D. Olivier, C. Villalba-Galea (2011). Controlling the Activity of a Phosphatase and Tensin Homolog (PTEN) by Membrane Potential J. Biol. Chem. 2011 286: 17945-17953. M110.201749.
176. Lacroix, J.J., A.J.Labro and F. Bezanilla (2011) Comments to the Editor. Response to R. Shirokov. Biophys J. 101:515-516.
177. Sandtner, W., B. Egwolf, F. Khalili-Araghi, J. Sanchez-Rodriguez, B. Roux, F. Bezanilla, M. Holmgren.(2011). Ouabain Binding Site in a Functioning Na+/K+ ATPase J. Biol. Chem., 286, 38177-38183.
178. Castillo JP, De Giorgis D, Basilio D, Gadsby DC, Rosenthal JJ, Latorre R, Holmgren M, Bezanilla F. (2011) Energy landscape of the reactions governing the Na+ deeply occluded state of the Na+/K+-ATPase in the giant axon of the Humboldt squid. PNAS. 108(51):20556-61.
179. Vargas E, Bezanilla F, Roux B.(2011) In search of a consensus model of the resting state of a voltage-sensing domain. Neuron.72(5):713-20.
180. Dekel, N., Priest, M.F., Parnas, H., Parnas, I., Bezanilla, F. (2012) Depolarization induces a conformational change in the binding site region of the M2 muscarinic receptor. PNAS. 109:285-290.
181. Gadsby DC, Bezanilla F, Rakowski RF, De Weer P, Holmgren M.(2012) The dynamic relationships between the three events that release individual Na⁺ ions from the Na⁺/K⁺-ATPase. Nat Commun.3:669.
182. Shapiro MG, Homma K, Villarreal S, Richter CP, Bezanilla F.(2012) Infrared light excites cells by changing their electrical capacitance. Nat. Commun.3:736.
183. Miceli F, Vargas E, Bezanilla F, Taglialatela M.(2012) Gating Currents from K(v)7 Channels Carrying Neuronal Hyperexcitability Mutations in the Voltage-Sensing Domain. Biophys J. 102(6):1372-82.
184. Lacroix, J.J. and F. Bezanilla  (2012) Tuning the Voltage-Sensor Motion with a Single Residue. Biophys J. 103, L23-L25
185. Labro, A. J., Lacroix, J.J., Villalba-Galea, C.A., Snyders, D.J. and Bezanilla, F.(2012) Molecular Mechanism for Depolarization-induced Modulation of Kv Channel Closure. J. Gen Physiol. 140:481–493.
186. Hyde, HC, Sandtner, W, Vargas, E, Dagcan, AT, Robertson, JL, Roux, B, Correa, AM & Bezanilla, F (2012) Nano-Positioning System for Structural Analysis of Functional Homomeric Proteins in Multiple Conformations. Structure 20, 1629–1640.
187. Lacroix, J.J, Pless, S.A., Maragliano, L., Campos, F.V, Galpin, J.D., Ahern, C.A., Roux, B. and Bezanilla, F. (2012). Intermediate State Trapping of a Voltage-Sensor. J.Gen.Physiol. 140:635-652.
188. Vargas, E., Yarov-Yarovoy, V. Khalili-Aragi, F., Catterall, W.A., Klein, M.L., Tarek, M., Lindahl, E., Schulten, K., Perozo, E., Bezanilla, F., Roux, B. Viewpoint: An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations. (2012) J.Gen.Physiol. 140:587-594.
189. Ruscic, K.J., Miceli, F., Villalba-Galea, C.A., Dai, H., Mishina, Y., Bezanilla, F., and Goldstein,S.A.N. (2013). IKs channels open slowly because KCNE1 accessory subunits slow the movement of S4 voltage sensors in KCNQ1 pore-forming subunits. PNAS, 110:E559-E566.
190. Shapiro, M.G., Priest, M.F., Siegel, P.H. and Bezanilla, F.(2013) Thermal Mechanisms of Millimeter-Wave Stimulation of Excitable Cells. Biophysical J 104(12):2622-2628.
191. Lacroix, J.J., Campos, F.V., Frezza, L. and Bezanilla, F. (2013). Molecular Bases for the Asynchronous Activation of Sodium and Potassium Channels Required for Nerve Impulse Generation. Neuron 79:651-657.
192. Capes, D., Goldschen-Ohm, M., Arcisio-Miranda, M., Bezanilla, F. and Chanda, B.(2013). Domain IV voltage-sensor movement is both sufficient and rate-limiting for fast inactivation in sodium channels. J. Gen. Physiol. 142:101-112.
193. Dang, B., Kubota, T., Mandal, K., Bezanilla, F., Kent, S.B.H. (2013) Native chemical ligation at Asx-Cys, Glx-Cys:chemical synthesis and high-resolution X-ray structure of ShK toxin by racemic protein crystallography. J. Am. Chem. Soc. 135:11911-11919.
194. Villalba-Galea, C.A, L. Frezza, W. Sandter and F. Bezanilla (2013) Sensing charges of the Ciona intestinalis voltage-sensing phosphatase. J. Gen. Physiol. 142:543-555.
195. Priest, M. F., J. J. Lacroix, C. A. Villalba-Galea and F. Bezanilla (2013) S3-S4 linker length modulates the relaxed state of voltage-gated potassium channel. Biophys. J. 105:2312-2322.
196. Bezanilla, F. and C.A. Villalba-Galea. (2013) The gating charge should not be estimated by fitting a two-state model to a Q-V curve. J.Gen.Physiol. 142:575-578.
197. Lacroix, , Jérôme J., H. Clark Hyde, Fabiana V. Campos, and Francisco Bezanilla (2014) Moving gating charges through the gating pore in a Kv channel voltage sensor. PNAS. 119:E1950-E1959.
198. Dalmas, Olivier, Walter Sandtner, David Medovoy, Ludivine Frezza, Francisco Bezanilla, and Eduardo Perozo. (2014). A repulsion mechanism explains magnesium permeation and selectivity in CorA. PNAS. 118:3002-3007.
199. Dalmas, Olivier, Pornthep Sompornpisut, Francisco Bezanilla1 & Eduardo Perozo.(2014) . Molecular mechanism of Mg2þ-dependent gating in CorA. Nature Comm. 5: Article number: 3590.
200. Dang, Bobo, Tomoya Kubota, Ana M. Correa, Francisco Bezanilla, and Stephen B. H. Kent. (2014). Total Chemical Synthesis of Biologically Active Fluorescent Dye-Labeled Ts1 Toxin. Angewandte Chemie. 53:1-6.
201. Kubota T, Lacroix JJ, Bezanilla F, Correa AM. (2014). Probing α-3(10) transitions in a voltage-sensing S4 helix. Biophys J. 2014 Sep 2;107(5):1117-28.
202. Treger JS, Priest MF, Iezzi R, Bezanilla F. (2014). Real-time imaging of electrical signals with an infrared FDA-approved dye. Biophys J. 2014 Sep 16;107(6):L09-12.
203. Dang B, Kubota T, Correa AM, Bezanilla F, Kent SB.(2014) Total chemical synthesis of biologically active fluorescent dye-labeled Ts1 toxin. Angewandte Chemie (International ed. in English). 53(34):8970-4. PubMed [journal]PMID: 24989851.
204. Sánchez-Rodríguez JE, Khalili-Araghi F, Miranda P, Roux B, Holmgren M, Bezanilla F. (2015) A structural rearrangement of the Na+/K+-ATPase traps ouabain within the external ion permeation pathway. Journal of molecular biology. 427(6 Pt B):1335-44. NIHMSID: NIHMS662284. PubMed [journal]PMID: 25637661 PMCID: PMC4457281
205. Carvalho-de-Souza JL, Treger JS, Dang B, Kent SB, Pepperberg DR, Bezanilla, F. (2015) Photosensitivity of neurons enabled by cell-targeted gold nanoparticles. Neuron. 2015; 86(1):207-17. NIHMSID: NIHMS667439. PubMed [journal]PMID: 25772189 PMCID: PMC4393361.
206. Castillo JP, Rui H, Basilio D, Das A, Roux B, Latorre R, Bezanilla F, Holmgren M. (2015) Mechanism of potassium ion uptake by the Na+/K+-ATPase. Nature Communications. 6, 7622. PMCID: PMC4515779.
207. Li Q, Shen R, Treger JS, Wanderling SS, Milewski W, Siwowska K, Bezanilla F, Perozo E. Resting state of the human proton channel dimer in a lipid bilayer.( 2015). Proceedings of the National Academy of Sciences of the United States of America.; 112(44):E5926-35. PMID: 26443860 PMCID: PMC4640771
208. Treger JS, Priest MF, Bezanilla F. (2015) Single-molecule fluorimetry and gating currents inspire an improved optical voltage indicator. eLife. 4. PubMed [journal]PMID: 26599732 PMCID: PMC4658195.
209. Labro AJ, Priest MF, Lacroix JJ, Snyders DJ & Bezanilla, F. (2015) Kv3.1 uses a timely resurgent K+ current to secure action potential repolarization. Nature Communications. 6, 10173. PMCID: PMC4703866.
210. Castillo JP, Sánchez-Rodríguez JE, Hyde HC, Zaelzer CA, Aguayo D, Sepúlveda RV, Luk LY, Kent SB, Gonzalez-Nilo FD, Bezanilla F, Latorre R.(2016). β1-subunit-induced structural rearrangements of the Ca2+- and voltage-activated K+ (BK) channel.Proceedings of the National Academy of Sciences of the United States of America; 113(23):E3231-9. PMID: 27217576 PMCID: PMC4988589.
211. Dang B, Kubota T, Mandal K, Correa AM, Bezanilla F, Kent SB.(2016). Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin. Angewandte Chemie (International ed. in English); 55(30):8639-42. NIHMSID: NIHMS807394. PMID: 27244051 PMCID: PMC5001624.
212. Jiang Y, Carvalho-de-Souza JL, Wong RC, Luo Z, Isheim D, Zuo X, Nicholls AW, Jung IW, Yue J, Liu DJ, Wang Y, De Andrade V, Xiao X, Navrazhnykh L, Weiss DE, Wu X, Seidman DN, Bezanilla F, Tian B. (2016). Heterogeneous silicon mesostructures for lipid-supported bioelectric interfaces. Nature materials; 15(9):1023-30. NIHMSID: NIHMS788971.PMID: 27348576 PMCID: PMC5388139.
213. Barchad-Avitzur O, Priest MF, Dekel N, Bezanilla F, Parnas H, Ben-Chaim Y.(2016). A Novel Voltage Sensor in the Orthosteric Binding Site of the M2 Muscarinic Receptor. Biophysical journal; 111(7):1396-1408.PMID: 27705763 PMCID: PMC5052511.
214. Kubota T, Durek T, Dang B, Finol-Urdaneta RK, Craik DJ, Kent SB, French RJ, Bezanilla F, Correa AM. (2017). Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET. Proceedings of the National Academy of Sciences of the United States of America. 2017; 114(10):E1857-E1865. PMID: 28202723 PMCID: PMC5347571.
215. Dang B, Shen R, Kubota T, Mandal K, Bezanilla F, Roux B, Kent SB.(2017). Inversion of the Side-Chain Stereochemistry of Indvidual Thr or Ile Residues in a Protein Molecule: Impact on the Folding, Stability, and Structure of the ShK Toxin. Angewandte Chemie (International ed. in English). 2017; 56(12):3324-3328. PMID: 28194851.
216. Kubota T, Correa AM, Bezanilla F. Mechanism of functional interaction between potassium channel Kv1.3 and sodium channel NavBeta1 subunit. (2017). Scientific Reports. 7: 45310. PMID 28349975 DOI: 10.1038/srep45310
217. Lee, Elizabeth E.L., Francisco Bezanilla. (2017). Biophysical Characterization of Genetically Encoded Voltage Sensor ASAP1: Dynamic Range Improvement. Vol 113, p2178–2181. 
218. Brugarolas, Pedro,  Jorge E. Sánchez-Rodríguez, Hsiu-Ming Tsai, Falguni Basuli, Shih-Hsun Cheng, Xiang Zhang, Andrew V. Caprariello, Jerome J. Lacroix, Richard Freifelder,  Dhanabalan Murali, Onofre DeJesus, Robert H. Miller, Rolf E. Swenson, Chin-Tu Chen, Peter Herscovitch, Daniel S. Reich , Francisco Bezanilla & Brian Popko. (2018). Development of a PET radioligand for potassium channels to image CNS demyelination. Scientific Reports 8:607 | DOI:10.1038/s41598-017-18747-3.
219. Mathur, Chhavi, Kory R. Johnson, Brian A. Tong, Pablo Miranda, Deepa Srikumar, Daniel Basilio, Ramon Latorre, Francisco Bezanilla & Miguel Holmgren. (2018). Demonstration of ion channel synthesis by isolated squid giant axon provides functional evidence for localized axonal membrane protein translation. Scientific Reports 8:2207 | DOI:10.1038/s41598-018-20684-8.
220. Carvalho-de-Souza, Joa˜o L. Bernardo I. Pinto, David R. Pepperberg, and Francisco Bezanilla. (2018) Optocapacitive Generation of Action Potentials by Microsecond Laser Pulses of Nanojoule Energy Biophysical Journal 114, 283–288.
221. Nanazashvili, Mikheil , Jorge E. Sánchez-Rodríguez, Ben Fosque, Francisco Bezanilla, Henry Sackin. (2018). LRET Determination of Molecular Distances during pH Gating of the Mammalian Inward Rectifier Kir1.1b. Biophysical Journal, Vol. 114, p88–97
222. Carvalho-de-Souza JL, Bezanilla F. (2018). Nonsensing residues in S3-S4 linker's C terminus affect the voltage sensor set point in K+ channels. J Gen Physiol. 150(2):307-321. doi: 10.1085/jgp.201711882.
223. Parameswaran, R, J. Carvalho-de-Souza, Y. W. Jiang, M. J. Burke, J. F. Zimmerman, K. Koehler, A. W. Phillips, J. Yi, E. J. Adams, F. Bezanilla, B. Z. Tian. (2018). Photoelectrochemical modulation of neuronal activity with free-standing coaxial silicon nanowires. Nature Nanotechnology, doi.org/10.1038/s41565-017-0041-7.
224. Bezanilla F. (2018)  Gating currents. J Gen Physiol. 2018 Jul 2;150(7):911-932. doi: 10.1085/jgp.201812090. Epub 2018 Jun 25. Review. PubMed PMID: 29941430; PubMed Central PMCID: PMC6028497.
225. Bezanilla F. (2018)  Influences: The Cell Physiology Laboratory in Montemar, Chile. J. Gen. Physiol. 2018 Vol. 150 No. 11 1464–1468. PMID: 30341084 PMCID: PMC6219681 DOI: 10.1085/jgp.201812157
226. Horng TL, Eisenberg RS, Liu C, Bezanilla F. (2018)  Continuum Gating Current Models Computed with Consistent Interactions. Biophys J. 2019 Jan 22;116(2):270-282. doi: 10.1016/j.bpj.2018.11.3140. Epub 2018 Dec 14. PubMed PMID: 30612713; PubMed Central PMCID: PMC6350011.
227. Carvalho-de-Souza JL, Nag OK, Oh E, Huston AL, Vurgaftman I, Pepperberg DR, Bezanilla F, Delehanty JB. (2019)  Cholesterol Functionalization of Gold Nanoparticles Enhances Photoactivation of Neural Activity. ACS Chem Neurosci. 2019 Mar 20;10(3):1478-1487. doi: 10.1021/acschemneuro.
228. Lee EEL, Bezanilla F. (2019)  Methodological improvements for fluorescence recordings in Xenopus laevis oocytes. J Gen Physiol. 2019 Feb 4;151(2):264-272. doi: 10.1085/jgp.201812189. Epub 2019 Jan 3. PubMed PMID: 30606741; PubMed Central PMCID: PMC6363413.
229. Jiang Y, Parameswaran R, Li X, Carvalho-de-Souza JL, Gao X, Meng L, Bezanilla F, Shepherd GMG, Tian B. (2019) Nongenetic optical neuromodulation with silicon-based materials. Nat Protoc. 2019 May;14(5):1339-1376. doi: 10.1038/s41596-019-0135-9. Epub 2019 Apr 12. PubMed PMID: 30980031; PubMed Central PMCID: PMC6557640.
230. Acarón Ledesma H, Li X, Carvalho-de-Souza JL, Wei W, Bezanilla F, Tian B. (2019) An atlas of nano-enabled neural interfaces. Nat Nanotechnol. 2019 Jul;14(7):645-657. doi: 10.1038/s41565-019-0487-x. Epub 2019 Jul 3. Review. PubMed PMID: 31270446; PubMed Central PMCID: PMC6800006.
231. Carvalho-de-Souza JL, Bezanilla F. (2019) Noncanonical mechanism of voltage sensor coupling to pore revealed by tandem dimers of Shaker. Nat Commun. 2019 Aug 8;10(1):3584. doi: 10.1038/s41467-019-11545-7. PubMed PMID: 31395867; PubMed Central PMCID: PMC6687735.
232. Bassetto CAZ Jr, Carvalho-de-Souza JL, Bezanilla F. (2019) Metal Bridge in S4 Segment Supports Helix Transition in Shaker Channel. Biophys J. 2019 Sep 5;. doi: 10.1016/j.bpj.2019.08.035. [Epub ahead of print] PubMed PMID: 31635788.
233. Rastogi,Sahil K., Raghav Garg, Matteo Giuseppe Scopelliti, Bernardo I. Pinto, Jane E. Hartung,Seokhyoung Kim, Corban G. E. Murphey, Nicholas Johnson, Daniel San Roman, Francisco Bezanilla, James F. Cahoon, Michael S. Gold, Maysam Chamanzar, and Tzahi Cohen-Karni.(2020). Remote nongenetic optical modulation of neuronal activity using fuzzy graphene.  PNAS June 16, 2020 vol. 117 no. 24 13339–13349. https://doi.org/10.1073/pnas.191992111.
234. Du X, Carvalho-de-Souza JL, Wei C, Carrasquel-Ursulaez W, Lorenzo Y, Gonzalez N, Kubota T, Staisch J, Hain T, Petrossian N, Xu M, Latorre R, Bezanilla F, Gomez CM. (2020). Loss-of-function BK channel mutation causes impaired mitochondria and progressive cerebellar ataxia. Proc Natl Acad Sci U S A. 2020 Mar 17;117(11):023-6034. doi: 10.1073/pnas.1920008117.Pub 2020 Mar 4. PubMed PMID: 32132200; PubMed Central PMCID: PMC7084159.
235. Moreno C, Yano S, Bezanilla F, Latorre R, Holmgren M. (2020). Transient Electrical Currents Mediated by the Na(+)/K(+)-ATPase: A Tour from Basic Biophysics to Human Diseases. Biophys J. 2020 Jul 21;119(2):236-242. doi: 10.1016/j.bpj.2020.06.006. Epub 2020 Jun 12. Review. PubMed PMID: 32579966; PubMed Central PMCID: PMC7376075.
236. Bassetto CA, Carvalho-de-Souza JL, Bezanilla F. (2021). Molecular basis for functional connectivity between the voltage sensor and the selectivity filter gate in Shaker K(+) channels. Elife. 2021 Feb 23;10. doi: 10.7554/eLife.63077. PubMed PMID: 33620313; PubMed Central PMCID: PMC7943188.
237. Catacuzzeno L, Franciolini F, Bezanilla F, Eisenberg RS. (2021). Gating current noise produced by Brownian models of a voltage sensor. Biophys J. 2021 Sep 21;120(18):3983-4001. doi: 10.1016/j.bpj.2021.08.015. Epub 2021 Aug 17. PubMed PMID: 34411574; PubMed Central PMCID: PMC8510977.
238. Priest MF, Lee EE, Bezanilla F. (2021). Tracking the movement of discrete gating charges in a voltage-gated potassium channel. Elife. 2021 Nov 15;10. doi: 10.7554/eLife.58148. PubMed PMID: 34779404; PubMed Central PMCID: PMC8635975.
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